DP - 2021 Jun 24, TA - Journal of Business Strategy Finance and Management PG - 125-140 VI - 1 IP - 5 4099 - jbsfm.org/article/19/ 4100 - jbsfm.org/article/19/ AB - This contribution of this study investigates how the use of the AE toolkit can take the lead to a greater appreciation of the university spin-off venture into the real world of work. Nevertheless, no conceptual framework can explain how the technology-market matching proceeds from one stage to another. A longitudinal survey design involving four focus groups was chosen to monitor the development process of group spin-off creation in context. Data collection is also derived from the literature review, in-depth interviews, and a series of workshops and focus group discussions on the Malaysian and Cambodian higher education sectors. Finding shows that the AE toolkit is organized around four mutually dependent themes: (1) the structure of an enterprising university and its culture, (2) university spin-offs (USOs) and applied research, (3) the attribute of academic entrepreneurs and entrepreneurial ecosystem, and (4) spin-off development and community engagements. These theories may offer a more comprehensive insight into the AE process in conjunction with each other. The beliefs of each notion hint at significant consequences for further research on AE and the world of work as a general rule.